Synthesis Workshop: Visible-light-mediated [2+2] Photocycloadditions with Marc Becker (Episode 35)

In this Research Spotlight episode, we're joined by Marc Becker (Schindler group), who takes us through his recently published work on azetidine synthesis via intermolecular [2+2] photocycloadditions.

Parent references:
Nat. Commun. 2019, 10, 5095.
Nat. Chem. 2020, 12, 898–905.

Behind the paper article
(Nature Research Chemistry Community)
https://go.nature.com/32odlIO

Other references (in order of appearance):
Reviews: Poplata, Tröster, Zou, Bach Chem. Rev. 2016, 116, 9748–9815.
D’Auria Photochem. Photobiol. Sci. 2019, 18, 2297–2362.

Fish, Brown, Evrard, Roberts Bioorg. Med. Chem. Lett. 2009, 19, 1871–1875.
Carreira, Fessard Chem. Rev. 2014, 114, 8257–8322.
Richardson, Becker, Schindler Chem. Sci. 2020, 11, 7553–7561.
Other intram. examples: a) Kumarasamy, Kandappa, Raghunathan, Jockusch, Sivaguru Angew. Chem. Int. Ed. 2017, 56, 7056–7061; b) Zhang et al. ACS Catal. 2020, 10, 10149–10156; c) Li, Großkopf, Jandl, Bach Angew. Chem. Int. Ed. 2020, accepted article. DOI: 10.1002/anie.202013276
Lu, Yoon Angew. Chem. Int. Ed. 2012, 51, 10329–10332.
Roth in PATAI’s Chemistry of Functional Groups (ed. Marek, I.) (Wiley, 2010); Patra, Bellotti, Strieth-Kalthoff, Glorius Angew. Chem. Int. Ed. 2020, 5 9, 3172–3177; Nicastri, Lehnherr, Lam, DiRocco, Rovis J. Am. Chem. Soc. 2020, 142, 987–998.
Strieth-Kalthoff, Henkel, Teders, Kahnt, Knolle, Gómez-Suárez, Dirian, Alex, Bergander, Daniliuc, Abel, Guldi, Glorius Chem. 2019, 5, 2183–2194.