Скачать или смотреть Dr. Andrius Baskys - Precision Med Starts Here: Integrating Clinical Genomics into Everyday Practice

The Global Grand Rounds session, hosted by Aisha, began with an introduction and housekeeping notes, including the recording of the presentation for later viewing on YouTube. Dr. Gregory Pecchia introduced the speaker, Dr. Andrius Baskys, highlighting his extensive background in psychiatry, neuroscience, and genomics. Dr. Baskys, a founder of MoodNote LLC, discussed his focus on integrating pharmacogenomics and next-generation sequencing into clinical practice, emphasizing the significance of genetic data in precision medicine.

Dr. Baskys presented two clinical cases to illustrate the practical application of genomic analysis. The first case involved a 65-year-old female with unresponsive high cholesterol levels due to an APOE44 genotype, which affects lipid metabolism and statin efficacy. The second case focused on a 72-year-old female with kidney disease linked to a rare CoQ8B gene variant. Both cases demonstrated how genomic insights can guide treatment decisions, such as alternative cholesterol-lowering agents and CoQ10 supplementation for kidney function improvement.

The presentation concluded with a discussion on the broader implications of genomic testing for personalized medicine, including its role in Alzheimer's therapies, hormone replacement therapy, and public health strategies. Dr. Baskys emphasized the need for interdisciplinary collaboration and training in bioinformatics for clinicians to effectively interpret genetic data. The session ended with questions from attendees and a reminder to create a Figure 1 account for CME credit, with future sessions scheduled for continued learning and collaboration.