Скачать или смотреть Chronic Symptoms Secretly Caused by MCAS, POTS, and Histamine Intolerance | Michelle Shapiro

Mysterious symptoms. Confusing diagnoses. Years of being dismissed. In this episode, Michelle Shapiro joins me to unpack the often misunderstood and overlooked world of mast cell activation syndrome (MCAS), histamine intolerance, postural orthostatic tachycardia syndrome (POTS), and hypermobility conditions.

Drawing from her own health journey and experience with thousands of clients, Michelle unpacks why conventional medicine often overlooks these complex, overlapping conditions—and how a root-cause, systems-based approach can lead to real healing. From nervous system regulation to low-histamine nutrition, this episode is a must-listen for anyone struggling with unexplained chronic symptoms.

You’ll learn:

• What MCAS is and why so many people are misdiagnosed
• The link between MCAS, POTS, and connective tissue disorders
• How nervous system regulation impacts immune reactivity
• Which foods trigger histamine flares and how to build a low histamine diet
• The surprising connection between hormones and histamine
• Why building muscle is critical for recovery from MCAS, POTS, and hypermobility

Whether you’re a clinician or someone living with these symptoms, this conversation offers insight, hope, and a roadmap forward.

Who is Michelle Shapiro?

Michelle Shapiro, RD, is a functional and integrative dietitian who has helped over 3,000 clients transform their health in the last 11 years. She leads a team of six expert nutritionists in her NYC-based virtual practice, specializing in complex cases like histamine issues, gut dysfunction, chronic anxiety, and weight concerns. She created the viral Histamine Essentials Webinar (now available on replay) and hosts the top-rated podcast Quiet the Diet, where she breaks down the science behind chronic illness in a way that actually makes sense. Michelle is the go-to expert for people who’ve tried everything and need a real plan.

This episode is brought to you by:

OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co
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Find Michelle Shapiro at:

Instagram -   / michelleshapirord  
Histamine Webinar Replay - https://michelleshapirord.com/histami...
Apply to work with Michelle’s team - https://airtable.com/appzFCkAqbbL4J2Q...

Find Me At:

Instagram:@drgabriellelyon
TikTok: @drgabriellelyon
Facebook: facebook.com/doctorgabriellelyon
YouTube:    / @drgabriellelyon  
X (Twitter): x.com/drgabriellelyon
Apply to become a patient – https://drgabriellelyon.com/new-patie...
Join my weekly newsletter – https://institute-for-muscle-centric-...
Get my book – https://drgabriellelyon.com/forever-s...

Timestamps:

00:00 – Introduction: Dismissed symptoms and hidden syndromes
01:43 – What is mast cell activation syndrome (MCAS)?
03:33 – Why histamine is the “loudest” chemical messenger
06:39 – MCAS symptoms: from flushing to anxiety
08:22 – Root causes: mold, toxins, and the “bucket” theory
11:15 – Diagnosing MCAS: blood, urine, and biopsy challenges
15:11 – Food patterns: how "healthy" foods trigger MCAS
16:53 – MCAS vs histamine intolerance: what’s the difference?
25:06 – High-histamine foods: what to avoid (and why)
27:37 – Nervous system & immune system: the feedback loop
29:45 – Pepcid and unexpected MCAS symptom relief
33:23 – Protocols: antihistamines, electrolytes, and nervous system support
35:27 – What to eat on a low-histamine diet
40:02 – Vasodilation, migraines, and POTS explained
42:41 – How POTS mimics cardiac symptoms
45:15 – MCAS and POTS: which to treat first?
48:25 – How to safely exercise with POTS and MCAS
53:20 – The role of hypermobility and Ehlers-Danlos Syndrome
59:23 – Estrogen, progesterone, and histamine sensitivity
1:03:39 – Why building muscle is essential for stability and recovery
1:07:00 – Infrared, cold therapy, and root-cause detox (after stabilization)
1:12:32 – Supplements: quercetin, resveratrol, PEA, and more
1:13:37 – Hope for recovery—and why belief matters
1:20:15 – Final reflections and message of resilience

Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.