Murine lupus protection and regulation of TLR7

Описание к видео Murine lupus protection and regulation of TLR7

In this episode Rachael Gordon and Haylee Cosgrove describe how NOX2 deficiency exacerbates lupus but the cell types and mechanisms by which NOX2 exerts protective effects remain unknown. They show that NOX2 regulates lupus by its function in macrophages/monocytes and B cells, where it modulates TLR7 signaling.

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