Thyroid Hormone Synthesis: Step-By-Step Pathway [Physiology Explained]

Thyroid hormone synthesis, physiology, pathway explained step-by-step! Animation of thyroid hormone production and regulation by the hypothalamus, anterior pituitary gland, and thyroid gland.

We discuss TRH release from the hypothalamus, TSH release from the anterior pituitary gland, and thyroid hormone synthesis and release from the thyroid gland.

Includes step-by-step walk through of how thyroid hormone is produced within the thyroid gland.

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Thyroid Hormone Synthesis:
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Timestamps:

00:00 Intro
00:44 Hypothalamic-Pituitary-Thyroid Axis
01:41 Step 1 - TRH Release (Hypothalamus)
02:24 Step 2 - TSH Release (Anterior Pituitary)
04:56 Step 3 - Thyroid Hormone Synthesis (Thyroid)
06:06 Step 3.1 - Thyroglobulin Production
06:29 Step 3.2 - Iodide Uptake
07:20 Step 3.3 - Iodide Oxidation
07:42 Step 3.4 - Thyroglobulin Iodination
08:37 Step 3.5 - MIT/DIT Coupling
10:12 Step 3.6 - Thyroglobulin Proteolysis
10:30 Step 4 - Thyroid Hormone Release
11:05 Flow Chart and Summary
11:35 Lecture Notes and Study Guide

Thanks for watching!

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