Скачать или смотреть Depression se bahar kaise aaye. How to overcome depression. How to increase memory in depression.

in this video Dr Mayank agrawal is explaining how to increase memory in depression patients. he is talking about certain medicines-

1- Bupropion
Class: Norepinephrine–Dopamine Reuptake Inhibitor (NDRI)
Main mechanism:
• Inhibits dopamine transporter (DAT) → ↑ extracellular dopamine, especially in prefrontal cortex (key for executive function & attention)
• Inhibits norepinephrine transporter (NET) → ↑ norepinephrine → better alertness, focus, mental energy
• Especially useful in depression with prominent cognitive slowing, low motivation, and also ADHD

2- Vortioxetine
Class: Multimodal antidepressant; serotonin modulator & stimulator
Main mechanism:
• Inhibits serotonin transporter (SERT) → ↑ serotonin
• Modulates serotonin receptors:

• ↑ BDNF (Brain-Derived Neurotrophic Factor) → improves synaptic plasticity
• Enhances long-term potentiation (LTP) → supports memory and learning
Cognition-related effect:

3- Duloxetine
Class: SNRI (Serotonin & Norepinephrine Reuptake Inhibitor)
Main mechanism:
• Blocks SERT → ↑ serotonin → improves mood, reduces anxiety
• Blocks NET → ↑ norepinephrine, especially at higher doses → better attention, energy & motivation
Cellular / neuroplasticity:
• ↑ BDNF with chronic use → supports synaptic remodeling
• Normalizes overactive limbic system → more efficient cognitive control by prefrontal cortex

4- Tianeptine
Class: Atypical antidepressant (structurally TCA, pharmacologically unique)
Main mechanism:
• Modulates glutamate transmission → stabilizes glutamatergic activity, especially under stress → protects neurons from excitotoxicity
• Reduces stress-induced glutamate excess → prevents dendritic atrophy in hippocampus & amygdala
• Regulates HPA axis → reduces cortisol overactivity → preserves cognitive function
Cellular / neuroplasticity:
• ↑ BDNF → supports neurogenesis & synaptic plasticity
• Protects hippocampal neurons → key area for declarative memory
Cognition-related effect:
• Improves learning, memory, attention especially in depression and stress-related disorders
• Effect is more neuroprotective & restorative, rather than pure cognitive enhancement

5 Injectable Ketamine
Class: NMDA receptor antagonist; dissociative anesthetic
Main mechanism:
• Non-competitive antagonist at NMDA receptors on GABAergic interneurons → ↓ inhibition → glutamate surge
• ↑ glutamate activates AMPA receptors → triggers BDNF release & mTOR signaling pathway
• Rapidly increases synaptogenesis & dendritic spine growth, especially in prefrontal cortex & hippocampus

Following topic are covered

depression se bahar kaise aaye
depression se kaise bahar nikle
depression se kaise nikale
depression se bahar kaise nikale
depression se kaise bahar nikale
depression se kaise bache
depression ko kaise dur kare
depression se bahar kaise nikle

#Bupropion #Vortioxetine #Tianeptine #Duloxetine #Ketamine #Cognition #Neuroplasticity #Memory #Attention #MentalHealth #DrMayankAgrawal

Check out our video playlist-

👉 Depression se bahar kaise nikale. Ketamine for depression in hindi.
   • Depression se bahar kaise nikale. Ketamine...  

👉 Serotonin kaise badhaye in hindi. How to increase serotonin levels naturally.
   • Serotonin kaise badhaye in hindi. How to i...  

👉Depression ki best medicine. डिप्रेशन के इलाज की सबसे अच्छी दवा- Psychiatrist in surat
   • Depression ki best medicine. डिप्रेशन के इ...  

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Dr Mayank Agrawal has done MD Neuropsychiatry from Sir JJ group of hospitals Mumbai. He has been trained in Deaddiction under Ministry of health and family welfare. He worked as a Nodal officer under District mental health program. He is renowned child psychiatrist and counselor. He is famous sexologist also. He has extensive experience in the assessment , diagnosis and treatment of psychiatric disorders across different age group. He has good skills in the use of therapeutic communication technique to establish rapport and deliver care to mentally ill patients.

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Disclaimer-The content on this video is offered only as information and it does not constitute solicitation or provision of Medical advice. The content here should not be used as a substitute for obtaining Medical advice from a licensed health care practitioner authorized to practice in your jurisdiction. You should always consult a qualified health care practitioner regarding any specific medical problem or issue.