Growth hormone - Should we use it in our body to build muscles ? Dr.Ravi Sankar Endocrinologist

📌𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-
  / drgbhanuprakash  

GH (growth hormone, somatotropin)

Direct effects
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↓ Glucose uptake into cells (↑ insulin resistance)
↑ Lipolysis
↑ Protein synthesis in muscle
↑ Amino acid uptake

Indirect effects:
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mediated by IGF-1 (insulin-like growth factor 1; originally called somatomedin C)
Growth stimulation
Anabolic effect on body
GH regulation
↑ GH secretion: exercise, deep sleep, puberty, hypoglycemia, CKD, thyroid hormone, estrogen, testosterone, and short-term glucocorticoid exposure
↓ GH secretion: glucose, somatostatin, somatomedin, free fatty acids, and chronic glucocorticoid therapy

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