BIH Lecture: Chantal Pichon

Lecture 30: "Messenger RNA, a Game Changer in Biomedicine: Where Do We Stand From Now?"

In the BIH Lecture on April 21, 2023, Chantal Pichon (University of Orléans, France) spoke about the success of mRNA vaccines, which has been made possible by advances in mRNA structure development, manufacturing and delivery systems. This success opens up an avenue for the development of innovative mRNA-based formulations envisioning different therapeutic applications in immunotherapy, regenerative medicine and gene editing. Those formulations are quite challenging due to the peculiar nature of mRNA. Current knowledge regarding strategies that her and other have proposed to overcome multiple biological barriers and to obtain a targeted delivery was summarized. Issues that she have to face when conducting those strategies was discussed. Last, she presented challenges that have to be tackled to fully prove mRNA mettle for therapeutic applications.

The lecture was moderated by Michael Schmück-Henneresse (BCRT).

About the Speaker: http://cbm.cnrs-orleans.fr/en/contact...

Further information on the BIH Lecture Series "Frontiers in Translational Medicine - Scientific and Structural Challenges": https://www.bihealth.org/de/aktuelles...