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Overview
Ankylosing spondylitis, also known as axial spondyloarthritis, is an inflammatory disease that, over time, can cause some of the bones in the spine, called vertebrae, to fuse. This fusing makes the spine less flexible and can result in a hunched posture. If ribs are affected, it can be difficult to breathe deeply.
Ankylosing spondylitis
As ankylosing spondylitis worsens, new bone forms as part of the body's attempt to heal. The new bone gradually bridges the gaps between vertebrae and eventually fuses sections of vertebrae together. Fused vertebrae can flatten the natural curves of the spine, which causes an inflexible, hunched posture.

Axial spondyloarthritis has two types. When the condition is found on X-ray, it is called ankylosing spondylitis, also known as axial spondyloarthritis. It is called non-radiographic axial spondyloarthritis when the condition can't be seen on X-ray but is found based on symptoms, blood tests, and other imaging tests.

Symptoms typically begin in early adulthood. Inflammation can also occur in other body parts — the eyes.

There is no cure for ankylosing spondylitis, but treatments can lessen symptoms and possibly slow the progression of the disease.

Symptoms
Early symptoms of ankylosing spondylitis might include back pain and stiffness in the lower back and hips, especially in the morning and after periods of inactivity. Neck pain and fatigue also are common. Over time, symptoms might worsen, improve, or stop at irregular intervals.

The areas most commonly affected are:

The joint between the base of the spine and the pelvis.
The vertebrae in the lower back.
The places where tendons and ligaments attach to bones, mainly in the spine, but sometimes along the back of the heel.
The cartilage between the breastbone and the ribs.
The hip and shoulder joints.







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