Скачать или смотреть Explaining Why Supplements are NOT The Answer for Cirrhosis of The Liver

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🧬 1. Supplements Aren’t a Cure & May Be Harmful
A 2017 Cochrane review concluded there's no evidence supporting antioxidant supplement use in alcoholic liver disease—and some supplements may even harm Very well Health+2Journal of Hepatology+2Verywell Health+2Wikipedia.


Up to 20% of liver injuries are attributed to herbal or dietary supplements, including green tea extract, anabolic steroids, and other multi-ingredient products Wikipedia.


For instance, high doses of vitamin A can lead to hypervitaminosis A and liver toxicity Wiley Online Library+15Wikipedia+15Espen+15.



🔬 2. Liver Detoxification: Phase I & II
The liver detoxifies through two essential enzyme pathways:
Phase I (cytochrome P450 enzymes): transforms toxins into reactive intermediates


Phase II (conjugation, e.g., with glutathione, sulfate): converts these into water-soluble forms for excretion The Times+2WJGNet+2Wiley Online Library+2


These enzyme systems require balanced nutrients (like B‑vitamins, amino acids, antioxidants), best provided by food—not high‑dose supplements.

🍎 3. Malnutrition in Cirrhosis & Food-Based Nutrition
Malnutrition is highly prevalent—affecting 50–90% of cirrhosis patients—and is linked to sarcopenia, infections, hepatic encephalopathy, and increased mortality The Times+2ejmo.org+2Wiley Online Library+2PMC+3PMC+3American College of Gastroenterology+3.


Early, specialized nutritional intervention improves outcomes: reduces hospital stay by ~30%, lowers mortality, and enhances muscle mass and nitrogen balance EASL-The Home of Hepatology.+2PMC+2American College of Gastroenterology+2.


Guidelines from ESPEN, ACG, EASL recommend high-energy, high-protein, complex carbs, and small frequent meals—not supplement megadoses EASL-The Home of Hepatology.+1Journal of Hepatology+1.



🌱 4. Whole Foods Over Supplements
Diets rich in plant-based foods (cereals, fruits, vegetables, legumes) protect the liver; red or processed meats may worsen liver disease PMC.


Whole foods supply nutrients in synergistic, balanced combinations that support detoxification, repair, and metabolic pathways.
🎯 Bottom Line
Supplements are not a substitute for medical management or nutrition in cirrhosis—and may be harmful.


The liver detox system depends on a complex, nutrient-rich diet.


Evidence-based guidelines consistently emphasize whole-food, balanced nutrition (high protein, complex carbs, plant-based sources), small frequent meals, and avoidance of harmful substances—not supplement megadoses.