Tramadol: What You Need To Know

Tramadol is a common analgesic that provides its effects by acting as an opioid and serotonin-norepinephrine reuptake inhibitor (SNRI). The opioid portion of its effects mainly comes from a metabolite, O-Desmethlytramadol (O-DSMT), while tramadol itself has a greater impact on monoaminergic systems.

Both the opioid and SNRI effects yield pain relief and mood changes.

It does have recreational effects, perhaps more so in those who are efficient at metabolizing tramadol to O-DSMT, but it's generally viewed as less intense than an opioid like morphine or diamorphine (heroin).

Other names = Ultracet; Ultram

TDC page with more information and references: https://thedrugclassroom.com/video/tr...

Reddit discussion:   / tramadol_what_you_need_to_know  
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Special thanks to BronzeManul for help with the chemistry section.

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Timestamps:

Medical effects: 00:38
Nonmedical effects: 05:22
Pharmacology and Chemistry: 12:23
How It's Used: 19:51
History: 20:23
Legality: 26:15
Safety: 26:25

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