Скачать или смотреть Role of Solvent in SN1 and SN2 Reactions?

Why does the solvent choice make or break your substitution reaction? In this video, we dive deep into how polar protic and aprotic solvents dictate whether a reaction follows the SN1 or SN2 pathway.

What You’ll Learn:

The SN2 Preference: How polar aprotic solvents (like DMSO, DMF, or Acetone) "free up" the nucleophile by preventing strong solvation, dramatically increasing SN2 reaction rates.

The SN1 Preference: Why polar protic solvents (like water or methanol) stabilize the transition state and carbocation intermediate, speeding up SN1.

Solvation Energy: A look at how hydrogen bonding shells can "cage" a nucleophile and hinder its reactivity.

Order of Nucleophilicity in Polar Aprotic vs Polar Protic Solvents

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