Скачать или смотреть Double cone blender| Mixing | Pharmaceutics | dkv pharma guidance

This Video Lecture covers the most important pharmaceutics topics double cone blender and it helpful for Pharma graduate and diploma students .

The double cone blender is used to produce homogeneous solid-solid mixture. Mixing is a common process step in the manufacture of pharmaceutical products like manufacturing powder, tablet capsule and also used in food, chemical, cosmetics, detergents, fertilizers manufacturing.
Principle:
 The mixing occurs due to tumbling motion.
 It provides a good cross flow with a rolling rather a sliding motion.
 Normally no baffles are required so that cleaning is simplified.

Construction:
 It consist double cone shape mixing (two cones joined as cylindrical section) tank.
 It rotates about an axis on the shaft.
 The conical shape at both ends allows uniform mixing and easy discharge.
 Inner part of tank is attached with blade.
 Mixing tank and blades are made of stainless steel.
Working:
 The powder is filled up to two third of volume of blender to ensure proper mixing.
 The rate of rotation should be 30-100 revolutions per minute.
 On rotation mixing occur due to tumbling motion.
 The product can be discharged from the bottom of the equipment.
 The mixing tank can be slanted freely at the angle of 0° to 360° degrees for discharging and cleaning purpose.
Advantages:
1. Easy to maintain and clean
2. There are no chances of clogging of material into corners
3. Large amount can be handled easily
4. It is efficient for mixing powders of different densities.
5. Wear on equipment is little

Disadvantages:
1. Not suitable for fine particles
2. Not suitable for particles with greater particle size difference due to less shear
Application
1. It is used for the homogeneous mixing of dry powders and granules (for tablets and capsule
2. formulations).
3. It can be used for pharmaceutical, food, chemical and cosmetic products etc.


#size sepration#
   • Pharmaceutical Engineering B.Pharm 3rd Sem...   ‘’ pharmaceutical engineering’’