Скачать или смотреть Pharmacokinetics: a drug's journey through the body;

Pharmacokinetics is the branch of pharmacology that describes what the body does to a drug from when it enters the body to when it exits. It involves four main process: absorption, distribution, metabolism and excretion, abbreviated as ADME. This video is a step by step journey through these processes.
00:00 Overview
00:37 Drug absorption
01:56 In the stomach
03:53 Pharmaceutical strategies to avoid destruction in the stomach
05:52 Small intestine
07:27 Crossing the intestinal epithelium
09:33 Drug distribution
10:52 Physicochemical properties and drug distributon
13:12 Volume of distribution
15:28 Factors affecting drug distribution
17:12 Drug metabolism
18:48 Phase 1 reactions
21:19 Phase 2 reactions
22:07 First pass metabolism
23:06 How to measure bioavailability
24:42 Drug excretion
25:23 Renal excretion of drugs
26:50 Drug excretion by the liver
28:52 Drug elimination; plasma half-time
30:45 Drug clearance
32:47 Summary