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Dr. Mario is a 1990 puzzle video game developed and published by Nintendo for the Nintendo Entertainment System and Game Boy. It was produced by Gunpei Yokoi and designed by Takahiro Harada. The soundtrack was composed by Hirokazu Tanaka.

It is a falling block puzzle game, in which the player's objective is to destroy the viruses populating the on-screen playing field by using colored vitamin capsules that are automatically tossed into the field by Dr. Mario. The player manipulates the falling capsules, to align the same colors, which destroys viruses. The player progresses through the game by eliminating all the viruses on the screen in each level.