What is Mycosis Fungoides? Symptoms, Causes, Treatment, Diagnosis: Cutaneous T Cell Lymphoma

What is Mycosis Fungoides? Symptoms, Causes, Treatment, Diagnosis: Cutaneous T Cell Lymphoma

What is Mycosis Fungoides?
Mycosis fungoides and Sézary syndrome are diseases in which lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin. Normally, the bone marrow makes blood stem cells (immature cells) that become mature blood stem cells over time.

What is mycosis fungoides caused by?
Causes. The cause of mycosis fungoides is unknown. Most affected individuals have one or more chromosomal abnormalities, such as the loss or gain of genetic material. These abnormalities occur during a person's lifetime and are found only in the DNA of cancerous cells.

How serious is mycosis fungoides?
For many people, the first sign of mycosis fungoides is a skin rash that is otherwise symptom-free. Without treatment, this rash may become itchy or develop ulcers. There is no cure for mycosis fungoides. With timely treatment, many people experience years with no symptoms.

What does a mycosis fungoides rash look like?
In its earliest form, mycosis fungoides often looks like a red rash (or scaly patch of skin). It begins on skin that gets little sun, such as the upper thigh, buttocks, back, belly, groin, chest, or breasts.

What is the best treatment for mycosis fungoides?
Treatment methods for mycosis fungoides include photochemotherapy (PUVA), topical steroids, short courses of UVB (during winter months), a drug known as topical nitrogen mustard (mechlorethamine), interferons, oral retinoid therapy, and/or photopheresis.

How long can you live with mycosis fungoides?
The overall survival and disease-specific survivals of our 525 patients with MF are shown in Figure 1. The median survival was 11.4 years, and the actuarial overall survival rates at 5, 10, and 30 years were 68%, 53%, and 17%, respectively. The median follow-up time was 5.5 years (range, 0.1-38.5 years)

Who is at risk for mycosis fungoides?
Age: Mycosis fungoides occurs most often in patients older than age 60, however can be seen at any age. Sex: Mycosis fungoides is twice as common in men as women.

Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, is the most common form of cutaneous T-cell lymphoma. It generally affects the skin, but may progress internally over time. Symptoms include rash, tumors, skin lesions, and itchy skin.

While the cause remains unclear, most cases are not hereditary. Most cases are in people over 20 years of age, and it is more common in men than women.

Does mycosis fungoides show up in blood work?
A sign of mycosis fungoides is a red rash on the skin. In Sézary syndrome, cancerous T-cells are found in the blood. Tests that examine the skin and blood are used to diagnose mycosis fungoides and Sézary syndrome

Is mycosis fungoides an autoimmune disease?
Mycosis Fungoides is a very rare disease, it's not a skin cancer although it manifests in the skin, it's actually a blood cancer that destroys your T Cells, it's an autoimmune disease, rendering your immune system useless.

Can mycosis fungoides go away on its own?
Classic mycosis fungoides

They can disappear spontaneously, stay the same size or slowly enlarge. They are most common on the chest, back or buttocks but can occur anywhere. They are often mistaken for more common skin conditions, such as eczema or psoriasis, sometimes for many years.

How fast does mycosis fungoides progress?
In the 32 patients with follicular mucinosis, disease progression was estimated to occur in 89% within 10 years after diagnosis vs 32% in the 277 patients without follicular mucinosis. The disease-related survival at 5 and 10 years was 81% and 36%, and the overall survival 75% and 21%, respectively.

How does mycosis fungoides spread?
Mycosis fungoides is a rare type of cutaneous T-cell lymphoma that begins on the skin and can spread to the body through the lymph nodes
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Is mycosis fungoides caused by a fungal infection?
The name mycosis fungoides is very misleading—it loosely means "mushroom-like fungal disease". The disease, however, is not a fungal infection but rather a type of non-Hodgkin's lymphoma.