Скачать или смотреть Large Intestine: Anatomy, Physiology, and Pathophysiology of Colonic Function.

Large Intestine: Gross Anatomy, Physiology, Pathology, and Clinical Correlates
Gross Anatomy
1. _Structure_: Consists of cecum, colon (ascending, transverse, descending, and sigmoid), rectum, and anus.
2. _Layers_: Mucosa, submucosa, muscularis externa, and serosa.

Physiology
1. _Water and electrolyte absorption_: Absorption of water, sodium, and potassium.
2. _Feces formation_: Storage and elimination of waste.
3. _Gut flora_: Presence of beneficial microorganisms.

Pathology
1. _Colorectal cancer_: Malignant tumors in colon or rectum.
2. _Diverticulitis_: Inflammation of diverticula (pouches) in colon wall.
3. _Inflammatory bowel disease (IBD)_: Conditions like ulcerative colitis and Crohn's disease.
4. _Irritable bowel syndrome (IBS)_: Functional disorder affecting bowel habits.

Clinical Correlates
1. _Colonoscopy_: Procedure to visualize colon and rectum.
2. _Surgical resections_: Removal of diseased portions of colon or rectum.
3. _Dietary modifications_: Changes in diet to manage symptoms.

Significance
1. _Waste elimination_: Large intestine plays crucial role in eliminating waste.
2. _Nutrient absorption_: Absorption of water, electrolytes, and short-chain fatty acids.
3. _Gut health_: Importance of maintaining healthy gut flora.

Created by: @hakimtheblackbutterfly Ft ‪@DavidashMays‬

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