Скачать или смотреть Altogen Labs SMMC-7721 Xenograft Service Liver Cancer

Altogen Labs http://altogenlabs.com provides xenograft services http://altogenlabs.com/xenograft-mode.... Cancer cell lines represent accurate molecular models of primary carcinomas and have proven to be potent tools in preclinical colon cancer research. The SMMC-7721 hepatocarcinoma cell line is derived from a Chinese male patient with hepatocellular carcinoma. The SMMC-7721 cell line is an excellent host for studying liver cancer.
The SMMC-7721 liver cell line is used to create the CDX (Cell Line Derived Xenograft) SMMC-7721 xenograft mouse model, a highly utilized CDX in cancer research to study new, low toxicity antitumor therapeutics or combinatorial therapies that incorporate the standard of care drugs. The SMMC-7721 xenograft model is essential for biomedical research related to human liver cancer.
Xenografting is the transplantation of tissue from one species into another.
Xenografting has been established as benchmark studies in pre-clinical cancer research.
Typically, immunodeficient mice serve as hosts for a wide variety of human tumors, effectively serving as models for human subjects.
Xenografting is a complete and accurate study of tumor growth and the activity of drug administration.

-SMMC-7721 Xenograft Model
Sample Cell Lines Available

-SMMC-7721 Xenograft Model
Advantages of Xenografting
Develop new therapeutic agents quickly, efficiently and cost-effectively
Evaluate the efficacy and toxicity of potential therapeutic agents
Evaluate target compound activity using in vivo system (human cells)
Predict cytotoxicity of cancer drugs

-SMMC-7721 Xenograft Model
Basic Xenograft Study
Xenograft studies can be designed to:
Identify lead compounds
Optimize dose schedules
Identify combination strategies

-SMMC-7721 Xenograft Model
Routes of drug administration:
Intratumoral
Intramuscular
Oral gavage
Intravenous
Intratracheal
Subcutaneous
Intraperitoneal
Continuous infusion
Intranasal
Using cutting-edge micro-injection techniques

-SMMC-7721 Xenograft Model
Following options are available for the SMMC-7721 xenograft model:
SMMC-7721 Tumor Growth Delay (TGD; latency)
SMMC-7721 Tumor Growth Inhibition (TGI)
Dosing frequency and duration of dose administration
SMMC-7721 tumor immunohistochemistry
Alternative cell engraftment sites (orthotopic transplantation, tail vein injection and left ventricular injection for metastasis studies, injection into the mammary fat pad, intraperitoneal injection)
Blood chemistry analysis
Toxicity and survival (optional: performing a broad health observation program)
Gross necropsies and histopathology
Positive control group employing cyclophosphamide, at a dosage of 50 mg/kg administered by intramuscular injection to the control group daily for the study duration
Lipid distribution and metabolic assays
Imaging studies: Fluorescence-based whole body imaging, MRI

-SMMC-7721 Xenograft Model
Altogen Labs’ team of scientists carries extensive experience in Xenograft model research.
Altogen Labs is compliant as a Good Laboratory Practices (GLP) environment, which is required by the FDA for pre-clinical research.
Our Altogen Labs’ Xenograft services are extensive, rigorous, and flexible.
Contact us to discuss Xenograft model details, timeline estimates, and price quotes!

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