Stem Cell Therapy For Kidney Disease

Stem cells, in general, are chemically attracted to injured areas of the body. Injured tissues release a class of so-called chemical messengers called cytokines. In the case of kidney disease, the kidneys will release cytokines specific to the kidneys to draw the stem cells to the kidney. The stem cells then regenerate and differentiate into the specific renal cells that are required for regenerate and repair the damaged tissue, such as parenchymal and glomeruli cells. Once the micro-circulation of the kidneys is restored, this lowers the blood pressure of the glomerulus. This, in turn, relieves the ischemia in the kidneys and therefore contribute to overall improvement of blood filtration and circulation. In cases of kidney disease secondary to autoimmune disease, along with enhancing immunity, stem cells are deployed in order to potentially eliminating the autoimmunity by inhibiting T-Cells, adjusting the immune system to work normally. The kidney lesion can be restored. Kidney regeneration is a challenging but promising strategy aimed at reducing the progression to end-stage renal disease (ESRD) and improving the quality of life of patients with ESRD. Adult stem cells are multipotent stem cells that reside in various tissues, such as bone marrow and adipose tissue.

The efficacy of mesenchymal stem cells (MSCs) in the recovery ofkidney function has been demonstrated.

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