Expi293: New Tools for Structural Biology and Difficult to Express Proteins

Presented By: Jon Zmuda, PhD

Speaker Biography: Jonathan Zmuda is a Director of Cell Biology at Thermo Fisher Scientific in Frederick, Maryland. Jon leads a team dedicated to discovering and developing new technologies and products useful for cell biology applications, including transient protein expression, advanced cell culture, and rare-cell analysis.

Webinar: Expi293: New Tools for Structural Biology and Difficult to Express Proteins

Webinar Abstract: In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell lines (e.g. GNTI-, Inducible and Inducible/GNTI- Expi293 cell lines) to allow for regulated expression and/or glycosylation of proteins, as well as an Expi293 Methionine-deficient system for metabolic labeling of proteins for NMR or multiwavelength anomalous dispersion (MAD). Together, these new tools significantly enhance the ability of researchers to produce proteins for structural biology analyses.

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