Intensivmedizinische Behandlung des akut auf chronischen Leberversagens Kapitel 1

Intensivmedizinische Behandlung des akut-auf-chronischen Leberversagens - Einleitung Definition Diagnose Stadien
Aktuelle Übersicht aus Intensive Care Medicine 2023:
Perricone, G., Artzner, T., De Martin, E. et al. Intensive care management of acute-on-chronic liver failure. Intensive Care Med 49, 903–921 (2023). https://doi-org/10.1007/s00134-023-07149-x

Acute-on-chronic liver failure (ACLF) is a clinical syndrome defined by an acute deterioration of the liver function associated with extrahepatic organ failures requiring intensive care support and associated with a high short-term mortality. ACLF has emerged as a major cause of mortality in patients with cirrhosis and chronic liver disease. Critical care management strategies and the option of liver transplantation should be balanced with futility considerations in those with a poor prognosis. This article provide insights on the current understanding of ACLF with emphasis on intensive care management.