Скачать или смотреть Antibiotic Resistance Alert: Streptococcus pneumoniae Acquires lsaC Gene Twice!

Streptococcus pneumoniae, lsaC gene, multidrug resistance, serotype 20, antibiotic resistance, pneumococcal disease.
Dive into groundbreaking research on how the multidrug resistance gene lsaC was independently acquired by Streptococcus pneumoniae serotype 20, multilocus sequence type 1257. This CDC study reveals two unique mechanisms of horizontal gene transfer, including interspecies recombination and transposition, leading to clindamycin resistance and potential implications for treatments like lefamulin.
Explore the phylogeny, mobile elements, and clinical significance in this detailed analysis from Emerging Infectious Diseases. Learn about the impact on vulnerable populations, such as adults experiencing homelessness and those with substance abuse issues.
Key findings include the 5.2-kb lsaC-containing element's integration into mobile elements, resistance phenotypes, and the broader context of pneumococcal surveillance.
Watch to understand the evolving threats of antibiotic resistance in pathogens and the importance of genomic monitoring.