What the Current Healthcare System is Missing?

Our body is a sack of chemicals & biochemical reactions & they have to work in synchrony to keep our body in homeostasis.

This complex biochemistry is what drives our health or disease. To understand each of the biochemical functions, we need to adopt a system biology approach to measure each of the interactions happening at the molecular level.

So what exactly is system biology? It is not driven by static DNA but ever evolving RNA which is nothing but expression of a gene stimulated by an external trigger be it stress, environment or our nutrition choices. There are three types of gene expression that takes place inside the body- the human genes expression( accounting for 1% of total genes expressed in our body), microbial genes expression ( 99% genes expression) & mitochondrial genes expression. How each of these gene expressions interact & influence each other is what keeps us healthy or sick.

Unfortunately, none of the healthcare solutions adopt a system biology approach rather have been too much obsessed with reductionist biology approach- treating every body organ separately & focussing on managing symptoms.

The external chemical solutions or fad diet interventions are too much focussed on managing the symptoms & just showing a neat graph without understanding the changes in chemistry behind these symptoms.

Symptoms which we try to address are nothing but the outcome of years or sometime decades of systemic inflammation. There are pre-disease biological signals but unfortunately none of these signals can be identified by standard of care diagnostic investigations. These biological signals are the outcome of interactions of change in gene expression of an individual’s microbiome or human cells. In order to deeply understand onset & progression of disease, we need to transition from reductionist biology to a system biology approach & measure each of these biochemical functions. Today's tak discusses this in detail.

We at Genefitletics, via our system biology platform offers a whole body biochemistry solution that measures these biochemical functions to identify these pre-disease signals & eliminate them through precision therapeutics. Future of preventative healthcare is here. More details here: www.genefitletics.com

Citations : https://www.cell.com/trends/molecular...
https://www.ncbi.nlm.nih.gov/pmc/arti...
https://www.ncbi.nlm.nih.gov/pmc/arti...