Histone Tail Clipping | Histone Modifications | Epigenetics | GATE/CSIR-NET

Описание к видео Histone Tail Clipping | Histone Modifications | Epigenetics | GATE/CSIR-NET

Histone tail clipping is a post-translational modification involving the proteolytic removal of the flexible N-terminal tails of histones. These tails are rich in lysine and arginine residues, serving as major sites for various post-translational modifications (PTMs), such as acetylation, methylation, phosphorylation, and ubiquitination. The clipping of these tails irreversibly alters chromatin structure and function by erasing existing histone marks and modifying nucleosome stability.

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