Скачать или смотреть Drug interactions pharmacology, ciprofloxacin and theophylline, drug interactions clinical pharmacy

💊 Ciprofloxacin inhibits cytochrome P450 1A2 (CYP1A2), the enzyme responsible for the metabolism of theophylline. This leads to increased theophylline levels in the blood.

🚨 Increased risk of theophylline toxicity, which can cause:
Nausea, vomiting
Insomnia, restlessness
Seizures
Cardiac arrhythmias

✅ Monitor theophylline levels closely when co-administering ciprofloxacin.
✅ Reduce theophylline dose if necessary to prevent toxicity.
✅ Consider alternative antibiotics (e.g., levofloxacin or azithromycin) if possible.
#theophylline #ciprofloxacin #antibioticstewardship #druginteractions #pharmacologylectures

Chapters:
0:00 - drug interactions pharmacology
0:10 - ciprofloxacin pharmacology
0:40 - theophylline pharmacology
1:09 - ciprofloxacin and theophylline drug interaction

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