mTOR Pathways: mTORC1 vs mTORC2 | Key Roles in Aging, Diseases, and Health

The mTOR Pathway plays a central role in regulating essential biological processes like cell growth, proliferation, and metabolism. This pathway is divided into two main complexes, mTORC1 and mTORC2, each with important functions in the body’s response to nutrients, growth factors, and environmental stress.

This video is taken from a podcast featuring our esteemed guest, Dr. Morgan Camp, who provides a thorough exploration of the mTOR signaling pathway and its complexities. Dr. Camp elaborates on the critical differences between mTORC1 vs mTORC2, explaining how each complex functions in regulating cellular activities. In particular, Dr. Camp highlights the activation and inhibition of mTORC1 and discusses the broader implications these complexes have for overall health, disease prevention, and longevity.

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Link To Full Podcast:    • Rapamycin: Uses, Benefits & Side Effe...  

In this video, we take a deep dive into what is mTOR, its multifaceted roles in the body’s cellular processes, and how it is crucial for maintaining healthy cell growth and metabolism. We also compare the functions of mTORC1 and mTORC2 in detail, breaking down their specific actions, including the critical role mTORC1 plays in regulating protein synthesis and cellular growth. Additionally, we examine how the activation and inhibition of mTORC1 can affect broader metabolic processes and health outcomes, particularly in relation to aging and disease prevention.

The mTOR pathway is integral to understanding how the body manages its balance between growth, energy use, and response to external stressors. By comparing the distinct roles of mTORC1 and mTORC2, this video sheds light on how these complexes contribute to cell growth, metabolism, and how they influence important processes such as protein synthesis, insulin signaling, and stress adaptation. Moreover, we touch on the health implications of their dysfunction, particularly in the context of chronic diseases like cancer and metabolic disorders.


00:00 Intro
00:42 What is mTOR Pathway
01:42 mTORC1 vs mTORC2
02:50 Actions of mTORC1
03:17 Activation of mTORC1 Pathway
03:48 Inhibition of mTORC1
04:50 Outro


Overall, this video provides an in-depth and comprehensive breakdown of the mTOR pathways, emphasizing the critical differences between mTORC1 and mTORC2 and how they regulate fundamental biological processes that are crucial for health. We offer clear insights into the mTOR pathway’s functions, how these pathways impact growth and metabolism, and their broader influence on aging and disease prevention, particularly with regard to cancer and other chronic conditions.


Who is Dr. Morgan Camp?
Dr. Morgan is an expert in Functional and Integrative Medicine with a Strong Emphasis in Bio-Identical Hormones, Longevity & Regenerative Medicine, Chronic Infections, Immune-Therapy, Detoxification, GI Health and Stress-Related illnesses.

To get in touch with Dr. Camp: https://www.drmorgancamp.com/


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This video is intended as General Advice ONLY. The posts or discussions in this video do not constitute medical advice. I expressly disclaim all liability with respect to actions taken or not taken based on any or all of the information or other content in this video. Please ALWAYS consult your Qualified General Practitioner or Doctor before changing your Diet or Medication or taking Supplements.


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