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Red Blood Cells

Red blood cell (erythrocyte) also known as "RBCs". RBCs are formed in the myeloid tissue or most commonly known as red bone marrow, although when the body is under severe conditions the yellow bone marrow, which is also in the fatty places of the marrow in the body will also make RBCs.

The formation of RBCs is called erythropoiesis ( erythro / red; poiesis / formation).

Red blood cells lose nuclei upon maturation, and take on a biconcave, dimpled, shape.

They are about 7-8 micrometers in diameter. There are about 1000x more red blood cells than white blood cells.

RBCs live about 120 days and do not self repair. RBCs contain hemoglobin which transports oxygen from the lungs to the rest of the body, such as to the muscles, where it releases the oxygen load.
The hemoglobin gets its red color from their respiratory pigments.


Shape

RBCS have a shape of a disk that appears to be “caved in” or almost flattened in the middle; this is called bi-concave.
This bi-concave shape allows the RBC to carry oxygen and pass through even the smallest capillaries in the lungs.
This shape also allows RBCs to stack like dinner plates and bend as they flow smoothly through the narrow blood vessels in the body.

RBCs lack a nucleus (no DNA) and no organelles, meaning that these cells cannot divide or replicate themselves like the cells in our skin and muscles.
RBCs have a short life span of about 120 days, however, as long as our myeloid tissue is working correctly, we will produce about 2-3 million RBCs per second. That is about 200 billion a day! This allows us to have more to replace the ones we lose.


Main Component

The main component of the RBC is hemoglobin protein, of which there are about 250 million per cell.
The word hemoglobin comes from "hemo" meaning blood and "globin" meaning protein.

Hemoglobin is composed of four protein subunits:-
polypeptide globin chains that contain anywhere from 141 to 146 amino acids. Hemoglobin is responsible for the cell’s ability to transport oxygen and carbon dioxide. Hemoglobin, iron, and oxygen interact with each other, forming the RBCs' bright red color. You can call this interaction by product oxyhemoglobin.

Carbon Monoxide binds with hemoglobin faster than oxygen, and stays bound for several hours, making hemoglobin temporarily unavailable for oxygen transport.

One red blood cell contains about 200 million hemoglobin molecules. If all this hemoglobin was in the plasma rather than inside the cells, blood would be so "thick" that the heart would have a difficult time pumping it through. The thickness of blood is called viscosity. The greater the viscosity of blood, the more friction there is, and more pressure is needed to force blood through.

Functions:-

The main function is the transportation of oxygen throughout the body and the ability of the blood to carry out carbon dioxide which is called carbamino – hemoglobin. Maintaining the balance of blood is important. The balance can be measured by the acid and base levels in the blood. This is called pH.

Normal pH of blood ranges between 7.35-7.45; this normal blood is called slightly Alkaline (less acidic than water). A drop in pH is called Acidic. This condition is also called Acidosis. A jump in pH higher then 7.45 is called "Alkalosis". To maintain the homeostasis (or balance,) the blood has tiny molecules within the RBC that help prevent drops or increases from happening.

Link:-

blood class 1st:-   • What is Blood l RBC/WBC/Platelets l Nsg Of...  

blood class 2nd:-   • What is Blood l Composition &Function l Ns...  

Pediatric class 1st:-   • Introduction of pediatrics  

Pediatric class 2nd (Rh incompatibility) :-
   • Rh Incompatibility & Erythroblastosis fetalis  

Tissue (nervous Tissue):-   • Tissue (Nervous Tissue)  

Nervous Tissue (Neuroglial):-    • Nervous Tissue ( Neuroglia)  

OBG class 1st:-   • OBG I Nursing Officer & Staff Nurse Online...  

Oxygen Inhalation part 1st-   • Oxygen Inhalation & Assessment Of Hypoxia  
Oxygen Inhalation part 2nd-   • Oxygen Inhalation, ABG Analysis & method o...  
Blood group system:-
   • Blood Group System ( ABO System)  

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