Beyond Widespread Pain: The Science Behind Fibromyalgia's Hidden Effects

Fibromyalgia is often characterized by widespread pain, but that's just the tip of the iceberg. This complex condition can also cause a variety of effects, impacting everything from sleep and digestion to mood and cognitive function.
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In this video, Gideon, a chronic pain specialist and fellow sufferer himself, delves into the latest scientific research on Fibromyalgia. You'll learn about:
The surprising science behind Fibromyalgia's hidden effects, like fatigue, brain fog, and gut issues.
Potential causes, including autoimmune mechanisms and nervous system dysfunction.
How these hidden effects can be linked and contribute to your overall experience of Fibromyalgia.
The path towards better treatments, fueled by a deeper understanding of the condition.
Don't suffer in silence. Watch this video and gain a deeper understanding of Fibromyalgia's hidden effects. Knowledge is power!

Chapters:
0:00 Fibromyalgia
1:42 Autoimmune Basis for Fibromyalgia?
3:30 Widespread Pain
4:33 Fatigue & Sleep Disturbances
5:17 IBS - Irritable Bowl Syndrom
5:56 Sensory Sensitivity
6:31 Autonomic Nervous System Dysfunction
7:01 Hypothalamic - Pituitary - Adrenal Dysfunction?

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Disclaimer: Pain.Pause.Live. is no substitute for a regular psychotherapy nor for medical treatment. We want to help you to gain and build up your quality of life despite chronic pain. If you suffer from chronic pain please turn to a doctor or a hospital for therapy.

Our mission is to provide you with scientifically proven, cutting edge psychological knowledge so you can regain responsibility over the quality of your life and lead into a direction of sense and meaning.
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Sources:
Kostine, M., Alvarez-Ciara, A., Olivan-Blazquez, B., Aguilar, H., Bondet, V., Delgado-Frias, E., ... & Arancibia-Carcamo, I. L. (2021). Fibromyalgia patient antibodies increase excitability of dorsal root ganglion sensory neurons. Journal of Clinical Investigation.
Sluka, K. A., & Clauw, D. J. (2016). Neurobiology of fibromyalgia and chronic widespread pain. Neuroscience, 338, 114-129.
Fallon, N., Chiu, Y., Nurmikko, T., & Stancak, A. (2018). Functional connectivity networks in the study of fibromyalgia. Journal of Integrative Neuroscience, 17(1), 1-8.
Sluka, K. A., & Clauw, D. J. (2016). Neurobiology of fibromyalgia and chronic widespread pain. Neuroscience, 338, 114-129.
Petersel, D. L., Dror, V., & Cheung, R. (2011). Central amplification and fibromyalgia: disorder of pain processing. Journal of neuroscience research, 89(1), 29-34.
Bigatti, S. M., Hernandez, A. M., Cronan, T. A., & Rand, K. L. (2008). Sleep disturbances in fibromyalgia syndrome: relationship to pain and depression. Arthritis Care & Research, 59(7), 961-967.
Minerbi, A., Gonzalez, E., Brereton, N. J., Anjarkouchian, A., Dewar, K., Fitzcharles, M. A., ... & Shir, Y. (2019). Altered microbiome composition in individuals with fibromyalgia. Pain, 160(11), 2589-2602.
Marum, A. P., Leitão, A. L., Brito, M. J., Variz, P., Alves, M., Vieira, L., ... & Bourbon, M. (2017). Increased intestinal permeability in fibromyalgia: a possible mechanism for pain transmission. Journal of Clinical Medicine, 6(12), 115.
Pimentel, M., Morales, W., Pokkunuri, V., Brikos, C., Kim, S. M., Kim, S. E., ... & Marsh, Z. (2015). Autoimmunity links vinculin to the pathophysiology of chronic functional bowel changes following Campylobacter jejuni infection in a rat model. Digestive diseases and sciences, 60(5), 1195-1205.
Wouters, M. M., Balemans, D., Van Wanrooy, S., Dooley, J., Cibert-Goton, V., Alpizar, Y. A., ... & Boeckxstaens, G. E. (2016). Histamine receptor H1-mediated sensitization of TRPV1 mediates visceral hypersensitivity and symptoms in patients with irritable bowel syndrome. Gastroenterology, 150(4), 875-887.
Kulshreshtha, P., & Deepak, K. K. (2013). Autonomic nervous system profile in fibromyalgia patients and its modulation by clinical variables. Clinical physiology and functional imaging, 33(2), 121-128.

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