Скачать или смотреть Why Do Selective Serotonin Reuptake Inhibitors (SSRIs) Cause Nausea and Diarrhea? | Pharmacology

Ever wondered why SSRIs like fluoxetine or sertraline can cause nausea, diarrhea, or stomach cramps, especially when you first start taking them? It’s not just a random side effect, it’s rooted in how serotonin works in your gut.
In this video, we break down the pharmacology of SSRI-induced gastrointestinal side effects. Learn how 5-HT₃ and 5-HT₄ receptors, the vagus nerve, and the gut-brain axis all contribute to symptoms like nausea, cramping, and diarrhea — and why these effects usually get better with time.
Perfect for pharmacology students, early-career healthcare professionals, or anyone curious about the science behind antidepressants and the gut.

Disclaimer: This YouTube video is not intended to provide diagnosis, treatment, or medical advice. The content provided in this video is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options. Information on this video should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products are not to diagnose, treat, cure, or prevent disease.

References:
1. Chu A, Wadhwa R. Selective Serotonin Reuptake Inhibitors. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NB...
2. Wang, Z., Li, H., Kang, Y., Liu, Y., Shan, L., & Wang, F. (2022). Risks of Digestive System Side-Effects of Selective Serotonin Reuptake Inhibitors in Patients with Depression: A Network Meta-Analysis. Therapeutics and clinical risk management, 18, 799–812. https://doi.org/10.2147/TCRM.S363404
3. https://calgaryguide.ucalgary.ca/sele...
4. https://psychopharmacologyinstitute.c...

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