Скачать или смотреть CRP(C REACTIVE PROTEIN).CRP BLOOD TEST.NORMAL RANGE,CAUSES OF HIGH CRP,Hs CRP ,HOW TO REDUCE CRP?

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CRP, or C-reactive protein, is a protein produced by the liver in response to inflammation in the body, and a CRP test is a blood test that measures the amount of this protein in your blood. High CRP levels can indicate inflammation caused by infections, autoimmune disorders, or injuries, but the test does not diagnose a specific disease. A doctor may use the CRP test to assess a patient's level of inflammation, monitor recovery from surgery or procedures, or screen for certain serious conditions like heart disease.
The liver releases CRP into the bloodstream in response to cytokines, which are released by white blood cells during inflammation. CRP helps the body's immune response by binding to damaged cells and harmful substances, activating the complement system, and helping to clear cellular debris.
A simple blood test is used to measure the amount of CRP, and it requires no special preparation. What high levels of CRP can mean
An elevated CRP level suggests that there is inflammation in your body, which could be caused by:
Infections: Such as a serious bacterial infection.
Inflammatory diseases: Like inflammatory bowel disease, rheumatoid arthritis, or autoimmune disorders.
Injuries or trauma: Such as from surgery or a significant physical injury.
Chronic conditions: Like some forms of cardiovascular disease, type 2 diabetes, or even certain cancers. A high CRP level can support the presence of an inflammatory disease but doesn't diagnose a specific one, as many conditions can cause it.
Monitoring:
It can be used to monitor patients after surgery or other procedures to detect infection.
Risk assessment:
For heart health, a high-sensitivity CRP (hs-CRP) test can help assess the risk of heart disease. C-reactive protein, also called CRP, is a protein made by the liver. The level of CRP increases when there's inflammation in the body. A simple blood test can check your C-reactive protein level.
A high-sensitivity C-reactive protein test, also called hs-CRP test, is more sensitive than a standard C-reactive protein test. That means the high-sensitivity test can find smaller increases in C-reactive protein than a standard test can.The hs-CRP test can help show the risk of getting coronary artery disease. In coronary artery disease, the blood vessels of the heart narrow. Narrowed blood vessels can lead to a heart attack. C-reactive protein test may be done to:Check for infection.
Help diagnose a chronic inflammatory disease such as rheumatoid arthritis or lupus.
Learn your risk of heart disease.
Learn your risk of a second heart attack.A high level of hs-CRP in the blood has been linked to an increased risk of heart attacks. Also, people who have had a heart attack are more likely to have another heart attack if they have a high hs-CRP level. But their risk goes down when their hs-CRP level is in the typical range.

An hs-CRP test isn't for everyone. The test doesn't show the cause of inflammation. So it's possible to have a high hs-CRP level that doesn't affect the heart.

An hs-CRP test may be most useful for people who have a 10% to 20% chance of having a heart attack within the next 10 years. This is known as intermediate risk. A healthcare professional can determine your risk using tests that look at your lifestyle choices, family history and overall health.C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via C1q.[5]

CRP is synthesized by the liver[6] in response to factors released by macrophages, T cells and fat cells (adipocytes).[7] It is a member of the pentraxin family of proteins.[6] It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.CRP binds to the phosphocholine expressed on the surface of bacterial cells such as pneumococcus bacteria. This activates the complement system, promoting phagocytosis by macrophages, which clears necrotic and apoptotic cells and bacteria.[18][13] With this mechanism, CRP also binds to ischemic/hypoxic cells, which could regenerate with more time. However, the binding of CRP causes them to be disposed of prematurely.[19][20] CRP binds to the Fc-gamma receptor IIa, to which IgG isotype antibodies also bind.[21] In addition, CRP activates the classical complement pathway via C1q binding.[22][23] CRP thus forms immune complexes in the same way as IgG antibodies.