Pemphigus-Pathogenesis,Histopathology,Clinical features and Treatment

#pemphigus#histopathology#clinicalfeatiresofpemphigus#oralpathology#pathology#oralmedicine#neetmds
Hi! Welcome to Medi study go!
This series is a detailed discussion on the skin lesions with the main focus on oral manifestations.
We also cover videos on exam oriented histopathology and mindmapping.

Link to the video on 1] Lichen planus-    • Lichen planus  
2]Erythema multiforme-    • Erythema multiforme  

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What is pemphigus vulgaris? Pemphigus vulgaris is a rare autoimmune skin disorder that causes blisters or bullae because there’s separation of skin cells.
Pemphigus vulgaris is an autoimmune muco-cutaneous condition occurring as a result of inappropriate production of auto-antibodies against the desmosomes holding the epithelial cells together, leading to an intra-epithelial blister formation. There is widespread ulceration of the skin, oral mucosal and other mucosal surfaces causing much pain and debilitation.

Though there are few treatments for pemphigus vulgaris, a rare disease, the Believe-PV trial of PRN1008 raises the possibility of a new, better option.
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