Скачать или смотреть Biotechnology: This Antibacterial Coating Stop Infections Before They Start

Tiny Spikes, Big Protection: A New Antibacterial Coating That Stops Infections Before They Start

Researchers at Chalmers University of Technology have developed an innovative antibacterial coating that kills bacteria by physically puncturing them before they can form biofilms. This breakthrough could help reduce hospital infections and limit the environmental damage caused by chemical-based antibacterial treatments.

Biofilms form when bacteria attach to surfaces and create a protective slime layer. These films grow on medical devices such as catheters and implants, as well as on ship hulls and industrial pipes. Once formed, biofilms are extremely difficult to remove and often lead to infections, equipment damage, and higher use of toxic chemicals.

Instead of using antibiotics or harmful metals, the Chalmers team used metal-organic frameworks (MOFs)—a Nobel Prize–winning material in chemistry—to create microscopic spikes on surfaces. These nanostructures are sharp enough to rupture bacterial cell membranes on contact, killing the bacteria instantly through mechanical force.

The researchers carefully engineered the spacing of the spikes to ensure maximum effectiveness. The coating can be applied to temperature-sensitive plastics, making it suitable for medical devices and large-scale production.

Because the method does not rely on chemicals, it avoids antibiotic resistance and environmental harm, offering a promising new path in the global fight against bacterial infections.

Read full article here: https://www.uncoverreality.in/2025/12...

Reference: Z. Cao, S. Pandit, F. M. A. Noa, et al. “ Mechano-Bactericidal Surfaces Achieved by Epitaxial Growth of Metal–Organic Frameworks.” Adv. Sci. 12, no. 46 (2025): e05976. https://doi.org/10.1002/advs.202505976

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