Скачать или смотреть Grapefruit and hair loss. The theory that explains everything.

Linked videos:
Oral minoxidil:
   • More evidence that oral minoxidil is dange...  
   • How oral minoxidil destroys your heart  
   • New evidence proves oral minoxidil for hai...  
   • The NY Times discovers the best hair loss ...  
   • Is sublingual minoxidil for hair loss safe...  
   • Oral minoxidil vs topical minoxidil.  Whic...  
Tretinoin and minoxidil:
   • How tretinoin works to fight hair loss  
Perfect dose of dutasteride:
   • What is the perfect dose of dutasteride fo...  

Sources:
1. Guo LQ, Fukuda K, Ohta T, Yamazoe Y. ROLE OF FURANOCOUMARIN DERIVATIVES ON GRAPEFRUIT JUICE-MEDIATED INHIBITION OF HUMAN CYP3A ACTIVITY.
2. Hung WL, Suh JH, Wang Y. Chemistry and health effects of furanocoumarins in grapefruit. J Food Drug Anal. 25(1):71-83. doi:10.1016/j.jfda.2016.11.008
3. Winchell GA, Gregoire S, Taylor AM, Hegland J, Hunninghake DB. Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine. The Journal of Clinical Pharmacology. 1993;33(10):967-970. doi:10.1002/j.1552-4604.1993.tb01931.x
4. Steiner JF. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride: Clinical Pharmacokinetics. 1996;30(1):16-27. doi:10.2165/00003088-199630010-00002
5. He K, Iyer KR, Hayes RN, Sinz MW, Woolf TF, Hollenberg PF. Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice. Chem Res Toxicol. 1998;11(4):252-259. doi:10.1021/tx970192k
6. Lin H lien, Kent UM, Hollenberg PF. The Grapefruit Juice Effect Is Not Limited to Cytochrome P450 (P450) 3A4: Evidence for Bergamottin-Dependent Inactivation, Heme Destruction, and Covalent Binding to Protein in P450s 2B6 and 3A5. J Pharmacol Exp Ther. 2005;313(1):154-164. doi:10.1124/jpet.104.079608
7. Bailey DG, Dresser G, Arnold JMO. Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? CMAJ. 2013;185(4):309-316. doi:10.1503/cmaj.120951
8. Ortiz de Montellano PR. Cytochrome P450-activated prodrugs. Future Med Chem. 2013;5(2):213-228. doi:10.4155/fmc.12.197
9. Paśko P, Rodacki T, Domagała-Rodacka R, Owczarek D. Interactions between medications employed in treating benign prostatic hyperplasia and food - A short review. Biomed Pharmacother. 2016;83:1141-1145. doi:10.1016/j.biopha.2016.08.021
10. Fatunde OA, Brown SA. The Role of CYP450 Drug Metabolism in Precision Cardio-Oncology. Int J Mol Sci. 2020;21(2):604. doi:10.3390/ijms21020604