Скачать или смотреть Electronic biosensors using Field-effect transistor as the transducer - part 1

Field Effect Transistors (FET) are common electronic components, but they are also suitable to build chemical (bio)sensors with in-built signal amplification. Electrochemists are hesitant to explore the possibilities of FET-based sensors, due to the hurdle of investment costs for characterization tools. This webinar aims to change that.

Two Presenters:
Dr. Lutz Stratmann (PalmSens) will discuss with FET expert Dr. Marcin Szymon Filipiak (Institute of Physical Chemistry, Polish Academy of Sciences) the basic principles of FET-based sensors, how they are characterized, what instruments to use, and some application examples.

There are two FET webinars:
-Part One will be on FET fundamentals, different types of FETs, and how to use the EmStat Pico to characterize them.
-Part two will be more focused on advanced FETs, for example, graphene as the semiconductor, the concepts of organic electrochemical FETs, etc.

For more information about the EmStat Pico Development Kit, please visit: https://www.palmsens.com/product/oem-...

For more information about measuring FETs, please visit:
https://www.palmsens.com/knowledgebas...

0:00 Introduction of speakers
2:00 Bipotentiostat to measure FETs
5:05 Cooperation for validation with Institute of physical chemistry
6:20 Introduction Marcin Szymon Filipiak
9:06 What are Field-effect transistors?
11:36 Two approaches to connect bipotentiostat to FET
15:00 Benchmarking of EmStat Pico
17:18 Three architectures for biosensing application
20:47 Extended-gate measurements with EmStat Pico
29:14 Advantage and challenge for FET-based biosensing
32:43 Receptor size in immunoFETs, surface engineering and PEG
40:50 Example measurement TSH spiked horse serum
44:10 Conclusion
47:18 Question 1: Is it possible to measure transconductance, using EIS with a PalmSens potentiostat?
48:30 Question 2: What is PEG's role? What is the sensing mechanism? Are you sensing the analyte's charge?
48:38 Question 3: Does 10nA make sense in bio-wearables in reality?
51:21 Question 4: 51:20 Can I use the PalmSens4 for measuring using FETs?
54:10 Question 5: How to connect a bipotentiostat to a FET?
57:12 Question 6: Why is the counter and reference electrode connected to each other?
58:55 Question 7: Can the EmStat Pico measure all three types of FET architectures for biosensing?
1:03:46 Question 8: How does PEG spacer enhance sensitivity and may it also contribute some charges?
1:05:58 Question 9: What are the crucial parameters when choosing your FET for a biosensor application?