Manufacturing of Tablets by wet Granulation method

Topics Covered
Steps involved in wet granulation method:
Milling of the drug and excipients
Weighing
Mixing including commonly used blenders
Wet massing 1. Low shear mixers/granulators,
2. High shear mixers/granulators,
3. Fluid-bed granulators/dryers,
4. Spray dryers, or
5. Extruders and spheronizers.
6. Spray-congealing
Drying of moist granules
Sizing the granulation by dry screening
Lubrication of granules
Compression of granules into tablets
2. Advantages and disadvantages of wet granulation

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Solid dosage form Tablets
Complete notes with explanation (video lectures)
1. Tablet introduction, Types of tablets
   • Tablet introduction, Types of tablets  

2. Tablet Ingredients in detail
   • Tablet Ingredients in detail  

3. How Quality control works in pharmaceutical industries. qc tests during tablet manufacturing
   • How Quality control works in pharmace...  

4. Hardness, Friability, Disintegration test, Quality control tests of tablets
   • Hardness, Friability, Disintegration ...  

5. Dissolution test, weight variation test, content uniformity test
   • Dissolution test, weight variation te...  

6. Pulverization /size reduction, Blending, Mechanism of granulation
   • Pulverization /size reduction, Blendi...  

7. Manufacturing of Tablets by wet Granulation method
   • Manufacturing of Tablets by wet Granu...  

8. Manufacturing of Tablets by Dry Granulation method
   • Manufacturing of Tablets by Dry Granu...  

9. Manufacture of Tablets by Direct Compression Method
   • Manufacture of Tablets by Direct Comp...  

10. Working and principle of tablet compression machine
   • Working and principle of tablet compr...  

11. Single Punch Tablet Press, eccentric press or single station press
   • Single Punch Tablet Press, eccentric ...  

12. Rotary Tablet Press(MultiStation Tablet Press), Components/Functional Parts of a Rotary Tablet Press
   • Rotary Tablet Press(MultiStation Tabl...  

13. MANUFACTURING DEFECTS OF TABLETS with pictures and their remedies
   • MANUFACTURING DEFECTS OF TABLETS with...  

14. Types of Tablet Coating Machines, why coating is important
   • Types of Tablet Coating Machines, why...  

15. Sugar coating process and problems in sugar coating process (Sugar coating defects, causes remedies)
   • Sugar coating process and problems in...  

16. Film Coating of tablets, Mechanism of film formation, Raw materials use in film coating
   • Film Coating of tablets, Mechanism of...  

17. Modified release Film coating in pharmaceuticals, Enteric coating, sustained release Film coating
   • Modified release Film coating in phar...  

18. Common Defects in Film Coating Process with Causes and Possible Solutions
   • Common Defects in Film Coating Proces...  

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