[#1] Hormônios: Estradiol, Progesterona e Testosterona | Dr. Vinícius Andrade

Hormônios: Estradiol, Progesterona e Testosterona

Sejam bem vindos a nova série do meu canal do YouTube sobre hormônios! Vou compartilhar um pouco de todo o meu conhecimento com vocês, solucionar dúvidas, e esclarecer os maiores mitos a respeito de todos os hormônios.

E pra começar trouxe um pouco de conhecimento a respeito dos hormônios sexuais: estradiol, progesterona e testosterona. Espero que vocês aproveitem e quaisquer dúvidas, deixem aqui nos comentários!

➤ Referências bibliográficas:

1. Decker DA, Pettinga JE, VanderVelde N, et al. Estrogen replacement therapy in breast cancer survivors: a matched‐controlled series. Menopause. 2003 Jul‐Aug;10(4):277‐85.
2. de Lignieres B, de Vathaire F, Fournier S, et al. Combined hormone replacement therapy and risk of breast cancer in a French cohort study of 3175 women. Climacteric.
2002;5:332‐340.
3. Jancin B. HRT Safe for Survivors of Early‐Stage Breast Ca. Family Practice News. 2001 Jun 1.
4. Natrajan PK, Gambrell RD. Estrogen replacement therapy in patients with early breast cancer. Am J Obstet Gynecol. 2002 Aug;187(2):289‐94.
5. Natrajan PK, Soumakis K, Gambrell RD Jr. Estrogen replacement therapy in women with previous breast cancer. Am J Obstet Gynecol. 1999 Aug;181(2):288‐95.
6. Levgur M. Hormone therapy for women after breast cancer. J of Reprod Med. 2004 Jul;49(7):510‐26.
7. Peters GN, Fodera T, Sabol J, et al. Estrogen replacement therapy after breast cancer: a 12‐year follow‐up. Ann Surg Oncol. 2001 Dec;8(10):828‐32.

• Zhu, Y., Zhang, Q., Zhang, W., Li, N., Dai, Y., Tu, J., ... & Wang, R. (2017). Protective effect of 17β-estradiol upon hippocampal spine density and cognitive function in an animal model ofvascular dementia. Scientific reports, 7, 42660.

• Wise, P. M., Suzuki, S., & Brown, C. M. (2023). Estradiol: a hormone with diverse and contradictory neuroprotective actions. Dialogues in clinical neuroscience.

1. Mahmoodzadeh, S., Leber, J., Zhang, X., Jaisser, F., Messaoudi, S., Morano, I., ... & Regitz-Zagrosek, V. (2014). Cardiomyocyte-specific estrogen receptor alpha increasesangiogenesis, lymphangiogenesis and reduces fibrosis in the female mouse heart post-myocardial infarction. Journal of cell science & therapy, 5(1), 153.
2. Tuomikoski, P., Salomaa, V., Havulinna, A., Airaksinen, J., Ketonen, M., Koukkunen, H., ... & Mikkola, T. S. (2016). Decreased mortality risk due to first acute coronary syndrome inwomen with postmenopausal hormone therapy use. Maturitas, 94, 106-109.
3. Lobo, R. A., Pickar, J. H., Stevenson, J. C., Mack, W. J., & Hodis, H. N. (2016). Back to the future: hormone replacement therapy as part of a prevention strategy for women at the onsetof menopause. Atherosclerosis, 254, 282-290.


• Sitruk-Ware, R. (2018). Non-clinical studies of progesterone. Climacteric, 21(4), 315-320

1. Gizard F, Robillard R, Gervois P, et al. Progesterone inhibits human breast cancer cell growth through transcriptional upregulation of the cyclin‐dependent kinase inhibitor p27Kip1 gene. FEBS Lett. 2005 Oct 24;579(25):5535‐41.
2. Campagnoli C, Abba C, Amgroggio S, Peris C. Pregnancy, progesterone and progestins in relation to breast cancer risk. J of Steroid Biochem& Molecular Biol. 2005;97:441‐450.
3. Foidart JM, Colin C, Denoo X, et al. Estradiol and progesterone regulate the proliferation of human breast epithelial cells. Fertil Steril. 1998 May;69(5):963‐9.
4. Fournier A, Berrino F, Riboli E, et al. Breast cancer risk in relation to different types of hormone replacement therapy in the E3N‐EPIC cohort. Int J Cancer. 2005 Apr 10;114(3):448‐54.
5. Wood CE, Register TC, Lees CJ, et al. Effects of estradiol with micronized progesterone or medroxyprogesterone acetate on risk markers for breast cancer in postmenopausal monkeys. Breast Cancer Res Treat. 2007 Jan;101(2):125‐34.

• Glaser, R. L., & Dimitrakakis, C. (2014). Rapid response of breast cancer to neoadjuvant intramammary testosterone-anastrozole therapy: neoadjuvant hormone therapy in breastcancer. • Menopause (New York, NY), 21(6), 673.
Dimitrakakis, C., & Bondy, C. (2009). Androgens and the breast. Breast cancer research, 11(5), 212.
• Glaser, R., & Dimitrakakis, C. (2015). Testosterone and breast cancer prevention. Maturitas, 82(3), 291-295.

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Capítulos
00:00 - Introdução
01:00 - Estradiol
04:00 - Benefícios do Estradiol
04:42 - Progesterona
06:24 - Benefícios da Progesterona
06:47 - Testosterona
09:00 - Benefícios da Testosterona

#estradiol #progesterona #testosterona #hormônios #drviniciusandrade