BioInsights Webinar: Elevate LNP optimization with Sunshine and Stunner

Problem

When working with LNPs, dialing in your process and flow parameters can be a tough nut to crack with one-by-one methods, and when you’re finally ready for clinical production, you’re stuck with all the re-optimization that comes with switching equipment. Tack on all the sample hungry experiments needed to I.D. your final lipid formulation, ideal flow rate, and buffers to improve stability, and you’re looking at tons of wasted time and resources.

Solution

Sunshine is the LNP production tool that beams through all the challenges of process development, LNP optimization, and continuous production. Sunshine’s flexibility across mixer types and process conditions is ideal for optimization work – while producing enough LNPs for any assay. Stunner handles all the analysis on particle size, PDI, particle count, and complete quantification of total RNA in less than 2 minutes from just 2 µL per sample. Stunner’s LNP applications detect aggregates like no other instrument and eliminates half the work of encapsulation efficiency assays.

Proof

In this seminar, we’ll show you how Sunshine and Stunner make the perfect pair when it comes to accelerating LNP optimization and development. We’ll compare multiple LNP formulations, flow rates, and cryoprotectant buffer conditions to see how size, polydispersity, aggregation, and RNA concentration stack up after production and after freeze-thaw cycling. Come see how Stunner’s unique approach to LNP sizing can help you spot aggregates you couldn’t see before and can help you save time, material, and hassle in your LNP workflow.