Скачать или смотреть Sequence Similarity Networks for the Protein Universe -- Ken Yokoyama

Our project is enabling generation of a library of precomputed sequence similarity networks for all Pfam families in the UniProtKB database for dissemination to the scientific community. At present, the Pfam database contains 16,295 families (Release 2.0; December 2015). To enable construction of the library, we are using Blue Waters to calculate 1) all-by all BLAST sequence relationships, 2) statistical analyses of the BLAST results; and 3) merged sets of input sequences based on sequence identity. We are working toward updating the library with an eight-week refresh cycle so that the library will remain current with the InterPro databases as new sequences are released. We will provide an update on our progress to achieve these goals.