Limit test for Heavy metal | Pharmaceutical inorganic chemistry B pharmacy 1st semester
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• HAP 1st Sem.
Inorganic chemistry
• Ph. Inorganic chemistry 1st sem
👉Pharmaceutical Analysis: • Pharmaceutical Analysis
👉Pharmaceutics
• Pharmaceutics
Syllabus..
Unit-I 10 Hours
Impurities in pharmaceutical Substances: History of Pharmacopoeia, Sources and
types of impurities, principle involved in the limit test for Chloride, Sulphate, Iron,
Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate.
General methods of preparation, assay for the compounds superscripted with
asterisk (*), properties and medicinal uses of inorganic compounds belonging to the
following classes.
Unit-II 10 Hours
Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in
pharmaceutical systems, preparation, stability, buffered isotonic solutions,
measurements of tonicity, calculations and methods of adjusting isotonicity.
Major extra and intracellular electrolytes: Functions of major
physiological ions, Electrolytes used in the replacement therapy: Sodium chloride*,
Potassium chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological
acid base balance.
Dental products: Dentifrices, role of fluoride in the treatment of dental caries,
Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement.
Unit-III 10 Hours
Gastrointestinal agents
Acidifiers: Ammonium chloride* and Dil. HCl.
Antacid: Ideal properties of antacids, combinations of antacids, Sodium Bicarbonate*,
Aluminum hydroxide gel, Magnesium hydroxide mixture.
Cathartics: Magnesium sulphate, Sodium orthophosphate Kaolin and Bentonite.
Antimicrobials: Mechanism, classification, Potassium permanganate, Boric acid,
Hydrogen peroxide*, Chlorinated lime*, Iodine and its preparations.
Unit-IV 08 Hours
Miscellaneous compounds
Expectorants: Potassium iodide, Ammonium chloride*.
Emetics: Copper sulphate*, Sodium potassium tartrate.
Hematinics: Ferrous sulphate*, Ferrous gluconate.
Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodium nitrite333.
Astringents: Zinc Sulphate, Potash Alum.
Unit-V 07 Hours
Radiopharmaceuticals: Radio activity, measurement of radioactivity, properties
of α, β, γ radiations, half-life, radio isotopes and study of radio isotopes- Sodium
iodide I131, storage conditions, precautions & pharmaceutical application of radioactive
substances
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