Скачать или смотреть What Most Has My Attention Right Now — Credible (vs. Bogus) Vagus Nerve Stimulation

Kevin J. Tracey, MD is president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, a pioneer of vagus nerve research and author of the recent book, The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes.

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[00:00] Start.
[00:38] Alleviating my skepticism about vagus nerve stimulation.
[05:21] SetPoint Medical receives FDA approval for vagus nerve stimulation device to treat rheumatoid arthritis.
[7:21] How Crohn's disease sufferer Kelly Owens went from a wheelchair to running up stairs in Amsterdam.
[14:47] Placebo effect concerns and what drove my interest in bioelectric medicine.
[19:52] Vagus nerve anatomy 101.
[25:57] What happens when the vagus nerve is stimulated.
[26:49] Accidental finding of brain-body inflammation connection.
[28:46] Bioelectronic medicine approach vs. pharmaceutical approach.
[31:25] Mice don't wheeze.
[33:22] Depression and inflammation connection: SSRIs may work through anti-inflammatory effects.
[36:00] My personal experience with vagus nerve stimulation and mood stability.
[37:40] The pros and cons of inflammation, and how controlling it may lead to even longer lifespans.
[44:09] Weighing the safety of VNS vs. biologics in cytokine suppression.
[49:55] Cold exposure, meditation, and breathing practices affecting the vagus nerve.
[52:32] A population-level increase in chronic inflammatory diseases.
[54:19] H. pylori: For when you can't blame stress, God, or the patient for that nagging ulcer.
[56:44] Stress, cortisol, and inflammation connections.
[59:13] SetPoint device vs. non-invasive alternatives for different patient populations.
[01:04:50] Auricular therapy's curious French origins.
[01:07:16] There's something fishy about this vestigial vagus nerve pathway.
[01:09:52] Brain imaging studies of ear stimulation.
[01:12:47] DARPA support and Geoff Ling's "What if it's yes?" attitude.
[01:15:47] Neurocognition and vagus nerve inputs.
[01:21:12] How Ulf Andersson turned his depression around with a TENS unit.
[01:25:55] Heart rate variability complexity and measurement challenges.
[01:27:09] A breathing exercise for directly controlling heart rate.
[01:29:27] Using a common antacid as a pharmacological vagus nerve stimulator during COVID.
[01:30:31] A call for more inflammation-based depression research.
[01:33:59] SSRIs and anti-inflammatory mechanisms in depression treatment.
[01:36:29] Interoception: The body's inflammatory signals reaching the brain via vagus nerve.
[01:37:32] Ulf's published protocol for TENS unit ear stimulation.
[01:38:46] VNS, acupuncture, fertility, and Martine Rothblatt.
[01:41:27] Chronic low back pain and an inflammatory overreaction analogy.
[01:42:50] Implications of Asya Rolls' engram research and inflammation memories in the brain.
[01:57:10] Cervical TENS vs. true VNS.
[02:01:51] Charles Sherrington's reflex theory and nervous system integration.
[02:06:55] Blue energy meditation and vagus nerve pathways with the Dalai Lama.
[02:11:21] Serious medical conditions vs. self-help approaches.

Corrections:
02:09:25 Dr. Tracey meant "Liz Blackburn."