Apoptosis - Introduction, Morphologic Changes and Mechanism

#apoptosis #pathology #cellinjury
Apoptosis, also called “programmed cell death” is the process where the cell regulates its own death through the production of certain enzymes. These enzymes cause degradation of nuclear and cytoplasmic DNA and the cell breaks into fragments called apoptotic bodies. Apoptotic bodies are then gobbled up by phagocytes.

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References and further reading:
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins Basic Pathology. 10th ed. Elsevier; 2018.
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and Cotran – Pathologic Basis of Disease. 8th Edition. Saunders Elsevier; 2010.
💡Abbas AK, Litchman AH, Pillai S. Cellular and Molecular Immunology. 8th Edition. Saunders Elsevier; 2015.
💡Elmore S. Apoptosis: A Review of Programmed Cell Death. Toxicol Pathol. 2007; 35(4): 495–516.
💡Apoptosis and Signal Transduction. Available at https://www.wehi.edu.au/wehi-tv/apopt....
💡Apoptosis. Available at http://www.onkoview.com/das-buch/kapi....

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