20.6 Synthesis and Reactions of Acid Halides | Organic Chemistry

Chad provides a summary of the synthesis and reactions of acid halides. This includes synthesis of acid bromides from carboxylic acids with PBr3 and the synthesis of acid chlorides from carboxylic acids with SOCl2. The reactions include several nucleophilic acyl substitution reactions including the conversion to acid anhydrides, esters, carboxylic acids, carboxylates, and amides. Also covered is the reaction with Grignard reagents, Gilman reagents, and reduction with LiAlH4 and Tri-tert-butoxyaluminum Hydride.

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00:00 Lesson Introduction
00:47 Synthesis from Carboxylic Acids with PBr3 or SOCl2
01:17 Nucleophilic Acyl Substitution
03:03 Reaction with Organometallics
04:15 Reduction with LiAlH4 and Lithium Tri-tert-butoxyaluminum Hydride

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