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IMPORTANT SAFETY INFORMATION (ISI)

VYLEESI® (bremelanotide injection) is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women who have not gone through menopause, who have not had problems with low sexual desire int he past, and who have low sexual desire no matter the type of sexual activity, the situation, or the sexual partner. The low sexual desire is troubling to them and is not due to medical, mental health, relationship problems, medicine or other drug use.

Do not use VYLEESI® if you have uncontrolled hypertension or known heart disease. The most common side effects include nausea, flushing, injection site reactions, headache and vomiting. Consult your healthcare professional for more information. See the Full Prescribing Information at Vyleesi.com or contact Cosette Pharmaceuticals, Inc. at 1-800-922-1038.

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