Harnessing the power of Genome Engineering

The Indiana University Genome Editing Center (IUGEC) provides state-of-the-art genome editing technologies by assisting with the generation of genetically modified cell lines and animal models in a time- and cost-effective manner.In this seminar, Dr. Pelletier will provide an overview of services offered, including CRISPR-based genome editing systems, conventional gene targeting in embryonic stem cells, and transgenesis to engineer genetically modified transformed cell lines, stem cells, and murine models.Examples of how these technologies can be used to identify and validate novel therapeutic targets, accelerate translational research, and advance precision medicine will be provided.