The Orville (season 3): Charly Burke sacrifices herself to destroy the weapon

"The Orville" is an American science fiction comedy-drama television series created by and starring Seth MacFarlane as series protagonist Ed Mercer, an officer in the Planetary Union's line of exploratory space vessels in the 25th century. The show is inspired primarily by the original "Star Trek" and its "Next Generation" successor, both of which it heavily parodies and pays homage to. It follows the crew of the starship USS Orville on their episodic adventures.

Season 3 Episode 9 - Domino

Cast:
Seth MacFarlane as Captain Ed Mercer
Adrianne Palicki as Commander Kelly Grayson
Michaela McManus as Teleya
Anne Winters as Charly Burke
Peter Macon as Lieutenant Commander Bortus
Jessica Szohr as Lieutenant Commander Talla Keyali
Mark Jackson as Isaac

Reference:
https://en.wikipedia.org/wiki/The_Orville
https://www.imdb.com/title/tt5691552/