Multisystem Inflammatory Syndrome in Children (MIS-C) Review

Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare complication of COVID-19 infection in children that results in a systemic inflammatory response.

In this quick review, I go over what we currently know about the epidemiology, pathophysiology, clinical features, and management of MIS-C, as well as some ways to differentiate MIS-C from Kawasaki Disease

This video is intended to be a quick review for students and providers before and during pediatric rotations

Sources:

Coronavirus disease 2019 (COVID-19): Multisystem inflammatory syndrome in children (MIS-C) clinical features, evaluation, and diagnosis (UpToDate)

Multisystem Inflammatory Syndrome in U.S. Children and Adolescents, NEJM

Multi-System Inflammatory Syndrome in Children (MIS-C) Following SARS-CoV-2 Infection: Review of Clinical Presentation, Hypothetical Pathogenesis, and Proposed Management, MDPI

Mubbasheer Ahmed et al, Multisystem inflammatory syndrome in children: A systematic review, EClinicalMedicine (2020)