UTI, Chronic Inflammation & Immune System Response: Dr. Indira Mysorekar

Dr. Indira Mysorekar is a Professor of Medicine whose lab group has made a number of significant discoveries in microbiology and microbial pathogenesis of UTI. One of these was the finding that E. coli can persist in reservoirs in the bladder and re-emerge to cause symptoms. This finding was a huge step forward for recurrent and chronic UTI research.


This interview answers the following questions and more:

👉 Can you see inflammation, biofilms, or an embedded infection via a cystoscopy?
👉 What is cystitis cystica and what does it look like on cystoscopy?
👉 How can chronic bladder inflammation and chronic UTI be differentiated?
👉 Could long term bladder inflammation lead to more serious conditions in the bladder?
👉 Is it possible to break the cycle of inflammation and infection?
👉 After a UTI, how long does inflammation in the bladder typically take to subside?
👉 Does repeated use of antibiotics have a negative impact on the immune system?
👉 How does the immune system deal with foreign objects such as an indwelling catheter?
👉 Are there any treatments or natural remedies that might provide helpful immune system support for those with chronic bladder infection?


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Scientific paper on D-mannose and cystitis cystica: https://journals.lww.com/fpmrs/abstra...

Scientific paper on estrogen therapy for UTI: https://journals.lww.com/fpmrs/abstra...


*About Dr. Indira U. Mysorekar*

Dr. Mysorekar is the inaugural E.L. Wagner Endowed Professor in Infectious Diseases in the Department of Medicine at Baylor College of Medicine (BCM). Dr. Mysorekar serves as Chief of Research in the Section of Infectious Diseases in the Department, Vice Chief of the Section, Professor in the Huffington Center on Aging and in the Department of Molecular Virology and Microbiology, and Director of an NIAID T32 Infectious Diseases Training Program. Indira grew up in India and Tanzania before moving to Sweden where she received her BS and MS degrees from the University of Lund, Sweden. She then moved to the United States and was awarded her PhD at Washington University School of Medicine in St. Louis where she went on to become the James P. Crane Endowed Professor of Maternal Fetal Medicine and Director of the Centre for Reproductive Health Sciences which she developed as a hub for outstanding translational research in women’s and reproductive health. The Mysorekar lab has made a number of novel and paradigm shifting discoveries in urogenital tract immunology, microbiology and microbial pathogenesis. Her research efforts have focused on increasing fundamental understanding of mechanisms underlying viral infections during pregnancy and urinary tract infections in older women and develop targeted therapeutic interventions to improve urogenital health.


*About Live UTI Free*

Live UTI Free is a patient advocacy and research organization. We provide research support, recruitment for research, and free resources for patient and clinician education on topics within women's pelvic health, with a focus on UTI. We do our best to provide patients with information about clinicians who specialize in recurrent and chronic UTI, in different regions. Patients, clinicians and researchers are welcome to reach out: https://liveutifree.com/contact


Post-production: Melissa Wairimu   / kreativlee_  


*Disclaimer*

The opinions presented in this video do not necessarily reflect the opinions of the Live UTI Free team. Live UTI Free does not endorse specific treatment approaches, clinicians or diagnostics methods. The content of this video does not provide medical advice. It is intended for informational purposes only. The medical and/or nutritional information is not a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen.