Optimizing brain health: Alzheimer's risk factors, APOE, & prevention strategies [AMA 46 sneak peek]

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In this sneak peek, we discuss:
00:00 - Intro
00:08 - Diagnosing Alzheimer's disease
05:36 - Biomarkers for Alzheimer’s disease, the C2N test, and other tools for diagnosis
11:25 - Genetic component of Alzheimer’s disease: genes that confer risk
16:59 - Understanding your APOE status and why it’s important to know
21:16 - The prevalence of Alzheimer’s disease and other forms of dementia, and who is at higher risk
24:45 - Can the risk of Alzheimer’s disease be decreased with behavioral changes?

In the full episode, we also discuss:
-Overview of modifiable behaviors that potentially play a role in risk reduction of neurodegeneration;
-Things that clearly impact brain health: smoking, alcohol, sleep, head injuries, blood pressure, and more;
-How nutrition impacts brain health: common diets, metabolic health, energy balance, and more;
-Comparing common diets: data showing the association between the incidence of Alzheimer’s disease and specific diets;
-Supplements: EPA and DHA, vitamin D, and B vitamins;
-Supplements: theracurmin, cocoa flavonols, and magnesium L-threonate;
-Impact of exercise on brain health, minimum effective dose, and the most important types of exercise;
-Challenging the mind with brain games—does it impact neurodegeneration?;
-The data on sauna and brain health;
-Oral health and its association with brain health;
-How reducing lipids can improve brain health and prevent neurodegeneration;
-The potential impact of hearing loss on brain health and neurodegeneration; and
-More.

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About:

The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 45 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more.

Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life).

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