Скачать или смотреть অ্যাজমা/COPD রোগীর জন্য ইনফ্লুয়েঞ্জা টিকা/important of influenza vaccine for COPD/Asthma patients.

Evidence of influenza vaccine effectiveness in preventing confirmed influenza among persons diagnosed with chronic obstructive pulmonary disease (COPD) is scarce. We assessed the average effect of influenza vaccination in the current and prior seasons in preventing laboratory-confirmed influenza in COPD patients. We carried out a pooled test-negative case–control design in COPD patients hospitalized or presented to primary healthcare centres with influenza-like illness who were tested for influenza in 2015/2016 to 2019/2020 seasons in Navarre, Spain. Influenza vaccination status in the current and 5 prior seasons was compared between confirmed-influenza cases and test-negative controls. Vaccination effect was compared between target patients for vaccination with and without COPD. Out of 1761 COPD patients tested, 542 (31%) were confirmed for influenza and 1219 were test-negative controls. Average effect for current-season vaccination in preventing influenza was 40% (95% CI 20–54%), and for vaccination in prior seasons only was 24% (95% CI –10 to 47%). Point estimates seemed higher in preventing outpatient cases (60% and 58%, respectively) than inpatient cases (37% and 19%, respectively), but differences were no statistically significant. Influenza vaccination effect was similar in target population with and without COPD (p = 0.339). Influenza vaccination coverage in control patients with COPD was 68.3%. A 13.7% of the influenza cases in patients with COPD could be prevented by extending the influenza vaccine coverage. Average effect of current-season influenza vaccination was moderate to prevent influenza in COPD persons. The increase of influenza vaccination coverage can still prevent COPD exacerbations.
Chronic obstructive pulmonary disease (COPD) is a highly prevalent condition and one of the main causes of years of life lost. Acute respiratory infections, especially influenza, are frequently causes of the exacerbation of COPD.Vaccination is the main preventive measure against influenza and its complications4. Since patients with COPD are at increased risk of hospitalization for influenza infections, annual influenza vaccination is recommended worldwide for them.However, the protective serum antibody response could be suboptimal in patients with COPD.

Influenza vaccine effectiveness in people with COPD was evaluated in observational studies against non-specific endpoints such as hospitalizations or deaths by all causes. These studies are prone to relevant bias because influenza virus infection is clinically indistinguishable from other respiratory infections not preventable by influenza vaccination.
The objective of this study was to evaluate the average effect and impact over five seasons of the influenza vaccination status in the current and prior seasons in preventing laboratory-confirmed influenza in persons with COPD. We also compared these estimates against those from the target population for influenza vaccination without COPD.Characteristics of COPD patients
A total of 1761 COPD patients with ILI were tested during the five influenza seasons, 1597 inpatients and 164 outpatients. Influenza virus was confirmed in 542 (31%) patients: 231 A/H3N2, 188 A/H1N1, 119 influenza B, two A not subtyped, one coinfected by influenza A/H3N2 and A/H1N1, and another coinfected by influenza A/H3N2 and B.Influenza vaccination effect in patients with COPD.Disclaimer:
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