Is It A Tummy Ache or A Tick Bite? Understanding Alpha-Gal Syndrome
How can a tiny tick bite make you allergic to your favorite steak or burger? What if your unexplained tummy aches are actually a delayed allergic reaction to the meal you ate hours ago? This is the strange reality of Alpha-Gal Syndrome.
In this fascinating episode of Allergy Actually, your bestie allergist moms – Dr. Kara Wada, Dr. Amber Patterson, and Dr. Meagan Shepherd – unravel the mysteries of this unique and increasingly common food allergy.
They dive into the surprising origin story of Alpha-Gal, explaining how it was discovered and why it's an allergy to a carbohydrate, not a protein, which turned the allergy world on its head. Learn how a tick bite transmits this allergy, why the reactions are dangerously delayed, and the crucial role of co-factors like exercise, alcohol, and high-fat meals. This is an essential guide to understanding, diagnosing, and managing this complex and often misunderstood condition.
In This Episode, You'll Learn:
The surprising origin story of Alpha-Gal Syndrome and its link to a chemotherapy drug.
How a tick bite actually causes a red meat allergy (and to other mammal products).
Why Alpha-Gal is a delayed reaction, with symptoms appearing 2-6 hours after eating.
The danger of "just testing" for Alpha-Gal after a tick bite and the risk of false positives.
The crucial role of "co-factors" (like alcohol, exercise, NSAIDs) in triggering a reaction.
Why Alpha-Gal can present as just chronic GI issues, leading to new gastroenterology guidelines.
Practical management strategies that focus on safely liberalizing the diet, not just strict avoidance.
Important tick prevention tips to protect yourself and your family.
EPISODE IN A GLANCE
00:10 Introduction to Alpha-Gal Syndrome
01:42 Historical Discovery of Alpha-Gal
03:30 How Alpha-Gal Transmission Occurs
04:41 Types of Mammals Affected
06:49 Clinical Presentation and Symptoms
08:22 Factors Affecting Reactions
11:35 Hidden Sources and Diagnosis
14:03 Impact on Quality of Life
16:08 Research Developments
17:59 Prevention and Future Concerns
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MENTIONED IN THIS EPISODE
Medical Concepts: Alpha-Gal Syndrome (Galactose-alpha-1,3-galactose), IgE-Mediated Allergy, Delayed Anaphylaxis, Co-factors, Histamine Bucket
Key Figures & Research: Dr. Thomas Platts-Mills, Cetuximab
Ticks: Lone Star Tick, Deer Tick, Chiggers
Hidden Sources: Carrageenan
ABOUT HOSTS
KARA WADA, MD
Dr. Kara Wada is a quadruple board-certified physician in allergy, immunology, and lifestyle medicine, and founder of the Immune Confident Institute. As a Sjogren’s patient and life coach, she combines modern medicine with lifestyle and mindset practices to help patients harness their body's ability to heal.
Website → https://drkarawada.com/
LinkedIn → / karawadamd
Instagram → / immuneconfidentmd
Facebook → / karawadamd
Youtube → / @drkarawada
TikTok → / immuneconfidentmd
AMBER PATTERSON, MD
Dr. Amber Patterson is a world-renowned allergy and immunology expert pioneering the future of immunotherapy. As the U.S. ambassador for ILIT™ (a 3-injection allergy shot protocol), she is redefining allergy care through her practice, Auni Allergy®, and the groundbreaking Auni ILIT Learning Network.
Website → https://auniallergy.com/
Instagram → / auniallergy
Instagram → / amber_patterson_md
Facebook → / auniallergy
Youtube → / @auniallergy
MEAGAN SHEPHERD, MD
Dr. Meagan Shepherd is a board-certified allergist and immunologist with nearly 15 years of experience specializing in advanced immunotherapy. She is known for her practical, evidence-based approach and her unique focus on "allergy-conscious living"—designing homes, habits, and lifestyles that improve her patients' quality of life.
Website → https://shepherdallergy.com/
LinkedIn → / meagan-shepherd-md-02b7776a
Instagram → / shepherdallergy
Facebook → / shepherdallergy
DISCLAIMER
The information in this podcast/video is for educational and informational purposes only and does not constitute medical advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
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